Investigation of miR-182 and miR-5187 acting as potential biomarkers for uLMCAD. ROC analysis of miR-182-5p (A) and miR-5187-5p (B); ROC analysis of miR182 (C) and miR-5187 (D) with adjusting the confounding influences of age, gender, Hypertension, MI, HDL, smoker and CCB; (E) correlation analysis between miR-182 and miR-5187; (F) ROC analysis of combined miR-182-5p and miR-5187-5p with adjusting the confounding factors. *, indicates adjust of age, gender, hypertension, MI, HDL, smoker and CCB. uLMCAD, unprotected left main coronary artery disease; ROC, receiver operating characteristic; MI, myocardial infarction; HDL, high density lipoprotein; CCB, calcium channel blockers.