Table 3. Characteristics of patients who required endotracheal intubation within 8 hours after flexible bronchoscopy.
| Parameters | Patient | |||||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | |
| Group | NIV | NIV | NIV | NIV | NIV | HFNC |
| Age, sex | 68 y, female | 31 y, female | 61 y, male | 68 y, female | 53 y, male | 53 y, male |
| SAPS II score | 32 | 12 | 39 | 38 | 25 | 39 |
| Immunosuppression | No | Yes | Yes | No | Yes | No |
| Final diagnosis | Bacterial pneumonia | Active interstitial lung disease | Pulmonary tuberculosis | Lung cancer | Viral pneumonia (CMV) | Pulmonary tuberculosis |
| PaO2 at baseline (mmHg) | 34 | 68 | 48 | 41 | 45 | 43 |
| PaO2 after NIV/HFNC (mmHg) | 67 | 254 | 62 | 85 | 88 | 75 |
| PaO2 after FB (mmHg) | 46 | 88 | 114 | 92 | 83 | 102 |
| PaO2 30 min after FB (mmHg) | 69 | 64 | 76 | 92 | 79 | 92 |
| Lowest SpO2 during FB (%) | 86 | 96 | 97 | 92 | 87 | 83 |
| Oxygen supplement after FB | NIV | NIV | NIV | NIV | NIV | NIV |
| Sampling techniques | BAL | Transbronchial biopsy | Transbronchial biopsy | BAL and transbronchial biopsy | BAL | BAL and transbronchial biopsy |
| Pneumothorax | No | No | No | Yes | No | Yes |
| Endotracheal tube insertion (h) | 4 | 4 | 2 | 7 | 3 | 4 |
| Hospital mortality | No | No | No | Day 11 | No | Day 7 |
BAL, bronchoalveolar lavage; CMV, cytomegalovirus; HFNC, high-flow nasal cannula; hrs, hours; FB, flexible bronchoscopy; mmHg, millimetres of mercury; NIV, non-invasive ventilator; PaCO2, arterial partial pressure of carbon dioxide; PaO2, arterial partial pressure of oxygen; SpO2, oxygen saturation by pulse oximeter; SAPS, Simplified Acute Physiology Score; sec, seconds; y, years.