Table 3. Risk factors of in-hospital mortality in patients with infection, by univariate and multivariate regression analysis.
| Variables | Control | Case | Model 1 | Model 2 | |||
|---|---|---|---|---|---|---|---|
| Crude OR (95% CI) | Adjusted ORa (95% CI) | Crude OR (95% CI) | Adjusted ORa (95% CI) | ||||
| Age groups (years), n | |||||||
| 18–64 | 381 | 25 | 1.00 (ref) | 1.00 (ref) | 1.00 (Ref) | 1.00 (Ref) | |
| 65–84 | 633 | 189 | 4.55 (2.94–7.04) | 3.21 (1.91–5.40) | 4.55 (2.94–7.04) | 3.22 (1.91–5.43) | |
| ≥85 | 349 | 139 | 6.07 (3.87–9.52) | 3.86 (2.22–6.71) | 6.07 (3.87–9.52) | 3.86 (2.21–6.71) | |
| BMI (kg/m2), n | |||||||
| 18.5–24.9 | 390 | 56 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | |
| <18.5 | 90 | 29 | 2.24 (1.36–3.71) | 1.72 (0.91–3.25) | 2.24 (1.36–3.71) | 1.76 (0.93–3.34) | |
| >24.9 | 229 | 32 | 0.97 (0.61–1.55) | 1.29 (0.72–2.30) | 0.97 (0.61–1.55) | 1.28 (0.71–2.28) | |
| Bedriddenb | 654 | 236 | 2.51 (1.83–3.45) | 1.63 (1.08–2.45) | 2.51 (1.83–3.45) | 1.65 (1.10–2.49) | |
| Comorbidities, n | |||||||
| Hypertension | 730 | 220 | 1.43 (1.13–1.82) | ||||
| Chronic heart disease | 409 | 141 | 1.44 (1.14–1.83) | 1.44 (1.14–1.83) | |||
| Chronic kidney disease | 53 | 25 | 1.88 (1.15–3.08) | 1.88 (1.15–3.08) | |||
| Malignancy | 175 | 99 | 2.65 (2.00–3.51) | 3.72 (2.55–5.45) | 2.65 (2.00–3.51) | 3.71 (2.53–5.42) | |
| Groups, n | |||||||
| Sepsis (vs. nonsepsis) | 636 | 299 | 6.33 (4.65–8.62) | 3.85 (2.70–5.50) | |||
| qSOFA (vs. qSOFA <2) | 337 | 303 | 18.45 (13.35–25.50) | 13.92 (9.87–19.63) | |||
| qSOFA(−)sepsis(−) | 594 | 16 | 1.00 (ref) | 1.00 (ref) | |||
| qSOFA(−)sepsis(+) | 432 | 34 | 2.71 (1.48–4.97) | 2.59 (1.39–4.83) | |||
| qSOFA(+)sepsis(−) | 133 | 38 | 10.61 (5.74–19.59) | 9.20 (4.86–17.38) | |||
| qSOFA(+)sepsis(+) | 204 | 265 | 48.23 (28.41–81.85) | 42.02 (24.31–72.64) | |||
a, adjusted for gender, age in age categories (15–64, 65–84, and ≥85 years), comorbidities such as malignancy, and the disease-related groups; b, BMI could not be calculated because these patients were bedridden. CI, confidence interval; OR, odds ratio; SOFA, sequential organ failure assessment.