Table 3.
Prediction of time to end of treatment (TTOT) in patients not progressing under letrozole
| Possible predictors | Hazard Ratio | 95% Confidence Interval | p-value | ||
|---|---|---|---|---|---|
| Lower Bound | Upper Bound | ||||
| Competing Risk Regression Model 1 | Age (in years) | 1.02 | 0.97 | 1.08 | 0.373 |
| BMI (kg/m2) | 1.02 | 0.94 | 1.11 | 0.563 | |
| Number of concomitant medications | 0.63 | 0.33 | 1.19 | 0.155 | |
| ECOG | 0.52 | 0.07 | 4,07 | 0.532 | |
| Time from diagnosis to therapy (in years) | 0.96 | 0.84 | 1.10 | 0.565 | |
| Adverse events within the first 30 days | 8.24 | 3.02 | 22.49 | < 0.0001 | |
| Competing Risk Regression Model 2 | Do you sometimes forget to take your medicine? | 0.81 | 0.20 | 3.24 | 0.762 |
| Do you take all your medicine always at the same time? | 1.15 | 0.23 | 5.68 | 0.864 | |
| Do you sometimes not take your medicine if you feel good? | 0.72 | 0.26 | 1.96 | 0.523 | |
| Do you not take your medicine at all if you feel worse due to illness? | 4.00 | 1.89 | 8.44 | 0.0003 | |
| On how many days in the past 30 days did you not take/forget to take your medicine? | 2.79 | 1.30 | 6.00 | 0.008 | |
| How satisfied were you with the information provided regarding endocrine treatment and its side effects? | 0.84 | 0.18 | 3.86 | 0.818 | |