Table 3.

Sample size required to obtain 90% disjunctive power and 90% marginal power when analysing two outcomes, after applying a Bonferroni correction

Standardised effect sizes for each of the 2 outcomes		Sample size required to obtain 90% DISJUNCTIVE power				Sample size required to obtain 90% MARGINAL power for each outcome
		Correlation between outcomes
Outcome 1	Outcome 2	0.2	0.4	0.6	0.8	Outcome 1	Outcome 2
0.2	0.2	402	436	475	522	622	622
0.2	0.3	237	251	264	274	622	278
0.2	0.4	145	150	154	156	622	157
0.2	0.5	96	98	99	100	622	101
0.3	0.3	179	194	211	232	278	278
0.3	0.4	126	135	144	152	278	157
0.3	0.5	89	93	97	99	278	101
0.4	0.4	101	109	119	131	157	157
0.4	0.5	78	84	90	96	157	101
0.5	0.5	65	70	76	84	101	101

Sample sizes provided are required per arm. A Bonferroni correction is applied for all calculations to account for the multiple comparisons