Table 1.
Cases (n=135) |
MRI controls (n=135) | OR (95% CI) for MRI controls | P value | Community controls (n=135) |
OR (95% CI) for community controls | P value | |
Age, years, median (IQR) | 53 (32–68) | 53 (32–68) | – | – | 53 (32–68) | – | – |
Female, n (%) | 61 (45) | 61 (45) | – | – | 61 (45) | – | – |
White, n (%) | 126 (93) | 123 (91) | 1.4 (0.6 to 3.4) | 0.49 | 119 (88) | 2.2 (0.8 to 5.7) | 0.11 |
Education | |||||||
Missing | 20 | 3 | – | – | 10 | – | – |
High school or less | 31 (27) | 31 (23) | 1.5 (0.6 to 3.3) | 0.31 | 47 (38) | 0.3 (0.1 to 0.7) | 0.003 |
Some college | 36 (31) | 37 (28) | 1.0 (0.5 to 1.8) | 0.77 | 33 (26) | 0.5 (0.2 to 1.1) | 0.05 |
College completion | 13 (11) | 24 (18) | 0.6 (0.2 to 1.3) | 0.18 | 23 (18) | 0.3 (0.1 to 0.8) | 0.007 |
Graduate education | 35 (30) | 40 (30) | (ref) | 22 (18) | (ref) | ||
HOUSES, Z (median, IQR) | −0.2 (−1.7, 2.3) | −0.8 (−2.6, 2.3) | 0.17 | −0.6 (−2.7, 1.8) | 0.05 | ||
HOUSES, n (%) | |||||||
Missing | 5 | 6 | – | – | 6 | – | – |
Q1 (lowest SES) | 26 (20) | 38 (30) | 0.5 (0.3 to 1.2) | 0.11 | 33 (26) | 0.6 (0.3 to 1.3) | 0.19 |
Q2 | 33 (25) | 30 (23) | 0.9 (0.5 to 1.8) | 0.81 | 34 (26) | 0.8 (0.4 to 1.7) | 0.52 |
Q3 | 35 (27) | 26 (20) | 1.1 (0.6 to 2.1) | 0.75 | 36 (28 | 0.8 (0.4 to 1.5) | 0.44 |
Q4 | 36 (28) | 35 (27) | (ref) | (ref) | 26 (20) | (ref) | |
Seasonal influenza vaccine, n (%) | 63 (47) | 62 (46) | 1.0 (0.6 to 1.7) | 0.89 | 50 (37) | 1.7 (1.0 to 3.1) | 0.06 |
PPSV23*, n (%) | 33 (24) | 39 (29) | 0.7 (0.3 to 1.4) | 0.29 | 30 (22) | 1.2 (0.6 to 2.5) | 0.59 |
Smoking exposure, n (%) | |||||||
Undocumented | 4 (3) | 3 (2) | – | – | 12 (9) | – | – |
Yes | 48 (36) | 67 (50) | 0.5 (0.3 to 0.9) | 0.01 | 52 (39) | 0.8 (0.4 to 1.3) | 0.33 |
No | 83 (62) | 65 (48) | (ref) | (ref) | 71 (53) | (ref) |
*Pneumococcal polysaccharide vaccine 23. Percentages may not add up to 100 due to rounding; ORs and p values for testing association of each variable with risk of glioma were estimated using conditional logistic regression models to take into account matching between cases and controls. Since age and gender were matching factors, their ORs and p values are not presented.
SES, socioeconomic status.