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. 2019 Jun 17;9(6):e025746. doi: 10.1136/bmjopen-2018-025746

Table 2.

Association of asthma with glioma cases compared with different set of controls (conditional logistic regression matching age and sex)

Cases
(n=135)
MRI controls (n=135) OR (95% CI) for MRI controls P value Community controls
(n=135)
OR (95% CI) for Community controls P value
Asthma PAC*, n (%) 21 (16) 36 (27) 0.5 (0.3 to 0.9) 0.02 17 (13) 1.3 (0.6 to 2.6) 0.48
Asthma activity, n (%)
 No asthma 114 (84) 99 (73) (ref) (ref) 118 (87) (ref) (ref)
 Inactive asthma 11 (8) 16 (12) 0.6 (0.3 to 1.3) 0.17 8 (6) 1.4 (0.5 to 3.8) 0.46
 Active asthma 10 (7) 20 (15) 0.4 (0.2 to 0.9) 0.03 9 (7) 1.1 (0.4 to 3.2) 0.79
Asthma control, n (%)
 No asthma 114 (84) 99 (73) (ref) (ref) 118 (87) (ref) (ref)
 Not poorly controlled asthma 19 (14) 29 (21) 0.6 (0.3 to 1.1) 0.11 14 (10) 1.5 (0.7 to 3.0) 0.31
 Poorly controlled asthma 1 (1) 7 (5) 0.1 (0.02 to 1.1) 0.05 3 (2) 0.3 (0.04 to 3.5) 0.38
Eczema, n (%) 11 (8) 17 (13) 0.6 (0.3 to 1.4) 0.22 7 (5) 1.7 (0.6 to 4.6) 0.32
Allergic rhinitis, n (%) 28 (21) 30 (22) 1.0 (0.5 to 1.6) 0.76 23 (17) 1.3 (0.7 to 2.4) 0.43
Family history of asthma, n (%)
 Undocumented 34 (25) 36 (27) 51 (38)
 Yes 12 (9) 15 (11) 0.8 (0.3 to 1.7) 0.49 7 (5) 1.5 (0.5 to 4.1) 0.46
 No 89 (66) 84 (62) (ref) (ref) 77 (57) (ref) (ref)

*PAC, predetermined asthma criteria.