FIG 1.

Experimental outline. C57BL6/J mice were infected by oral gavage with wild-type (PMSS1), straight-rod mutant (Δcsd6), or csd6 complemented H. pylori bacteria or mock infected with broth. At the indicated time points, the stomach was removed and one-third used to determine bacterial load, one-third for pathology evaluation, and one-third for bacterial localization within glands. C, corpus; A, antrum; PFA, paraformaldehyde; NBF, neutral buffered formalin; H&E, hematoxylin and eosin; IHC, immunohistochemistry.