. 2019 Mar 7;104(8):3355–3361. doi: 10.1210/jc.2018-02313

Table 1.

Baseline Clinical Characteristics and Reproductive Hormones

	PCOS-d (n = 48)	OB-g (n = 30)	NW-g (n = 22)	P	PCOS-d vs OB-g	PCOS-d vs NW-g	OB-g vs NW-g
Age, y	9.7 ± 1.3^a (8.0–12.3)	10.3 ± 1.1 (8.3–12.3)	10.3 ± 1.1 (8.3–12.7)	0.05	0.09	0.14	0.99
BMI percentile	80 ± 23 (16–99)	99 ± 1 (97–99)	50 ± 19 (19–84)	NA	NA	NA	NA
BMI z score	1.1 ± 0.9 (−1.0 to 2.5)	2.4 ± 0.2 (1.9–2.9)	0.0 ± 0.5 (−0.9 to 1.0)	<0.0001	<0.0001	<0.0001	<0.0001
Tanner breast stage	44% I^b	33% I	32% I	0.01^c	NA	NA	NA
	40% II	13% II	27% II
	16% III	54% III	41% III
Tanner pubic hair stage	67% I	33% I	32% I	0.01^c	NA	NA	NA
	29% II	33% II	45% II
	2% III	33% III	18% III
	2% IV		5% IV
Total T,^d ng/dL	8 ± 6 (1–30)	9 ± 6 (1–22)	9 ± 8 (2–33)	0.53	NA	NA	NA
SHBG,^e nmol/L	54 ± 31 (9–180)	22 ± 10 (7–54)	71 ± 22 (38–121)	<0.0001	<0.0001	0.005	<0.0001
Free T,^f ng/dL	0.13 ± 0.12 (0.01–0.58)	0.22 ± 0.15 (0.03–0.58)	0.10 ± 0.10 (0.02–0.40)	0.0002	0.19	0.01	0.0001
AMH,^g ng/mL	3.28 ± 2.34 (0.13–13.00)	1.22 ± 0.72 (0.20–3.03)	2.08 ± 0.94 (0.79–4.52)	<0.0001	<0.0001	0.10	0.07
DHEAS,^h ng/mL	493 ± 358 (91–1730)	635 ± 349 (179–1555)	549 ± 362 (145–1770)	0.34	NA	NA	NA
Androstenedione,ⁱ ng/mL	0.47 ± 0.37 (0.13–1.27)	0.57 ± 0.37 (0.11–1.77)	0.50 ± 0.41 (0.11–1.78)	0.52	NA	NA	NA
Estradiol,^j pg/mL	13 ± 11 (4–59)	20 ± 14 (7–76)	14 ± 10 (5–43)	0.09	NA	NA	NA

P values listed from analysis of covariance correcting for age and Tanner breast stage unless noted otherwise. BMI percentiles reported for descriptive purposes only. Statistical assessment for differences between the groups performed only on BMI z score. To convert DHEAS from ng/mL to nmol/L, multiply by 2.714; androstenedione from ng/dL to nmol/L, multiply by 0.0349; and estradiol from pg/mL to pmol/L, multiply by 3.671.

Abbreviation: NA, not applicable.

^{^a}

Mean ± SD (range).

^{^b}

Percentage of subjects included in each group is noted.

^{^c}

The categorical variables Tanner breast and pubic hair stages were analyzed by Fisher’s exact test.

^{^d}

Total T levels missing in three PCOS-d.

^{^e}

SHBG levels missing in two PCOS-d.

^{^f}

Free T levels missing in four PCOS-d.

^{^g}

AMH levels missing in nine PCOS-d, seven OB-g, and four NW-g.

^{^h}

DHEAS levels missing in six PCOS-d and two NW-g.

^ⁱ

Androstenedione levels missing in 28 PCOS-d.

^{^j}

Estradiol levels missing in 12 PCOS-d, six OB-g, and four NW-g.