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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Resuscitation. 2019 Apr 2;139:343–350. doi: 10.1016/j.resuscitation.2019.03.035

Table 3.

Predictive value of the European Resuscitation Council/European Society of Intensive Care Medicine (ERC/ESICM) guideline

Discharge outcome
TP, N FP, N TN, N FN, N p FPR, % (95% CI) Sensitivity, % (95% CI)
“Very likely” poor outcome, day 3 33 0 24 150 0.02 0 (0–14) 18 (13–24)
“Very likely” poor outcome, day 4 32 0 24 133 0.02 0 (0–14) 19 (14–26)
“Very likely” poor outcome, day 5 26 0 24 119 0.03 0 (0–14) 18 (13–25)
“Likely” poor outcome 48 0 24 135 0.0016 0 (0–14) 26 (20–33)
6 month outcome
TP, N FP, N TN, N FN, N p FPR, % (95% CI) Sensitivity, % (95% CI)
“Very likely” poor outcome, day 3 33 0 33 141 0.003 0 (0–10) 19 (14–25)
“Very likely” poor outcome, day 4 32 0 33 124 0.002 0 (0–10) 21(15–28)
“Very likely” poor outcome, day 5 26 0 33 110 0.003 0 (0–10) 19 (13–27)
“Likely” poor outcome 48 0 33 126 <0.001 0 (0–10) 28 (21–35)

Abbreviations: TP = true positive; FP = false positive; TN = true negative; FN = false negative; FPR = false positive rate

P values are calculated for contingency tables.

a

Based on one or both of the following: 1) no pupillary and corneal reflexes, and/or 2) bilaterally absent N20 potentials on somatosensory evoked potentials (SSEP)

b

Defined as two or more of the following, with earliest prognostication beginning at 72 hours: 1) myoclonic status epilepticus ≤ 48 hours after return of spontaneous circulation (ROSC), 2) high neuron specific enolase levels at 48–72 hours after ROSC, 3) unreactive burst-suppression or status epilepticus on EEG, 4) diffuse hypoxic-ischaemic brain injury on brain CT (≤ 24 hours after ROSC) or MRI (days 2–5)