| •Monro-Kellie Hypothesis volume equilibrium between intracranial compartments of blood, CSF, brain parenchyma • CPP = MAP - ICP •Ohm’s Law: CBF =MAP - ICP /Resistance •Poiseuille’s Law: Resistance α1/radius4 Q = πr4 ΔP/ 8 ηL |
• Autoregulation maintaining CBF over a range of CPP • Compliance = ΔV/ΔP • Elastance = ΔP/ΔV • PVI (ml) =V/1og(Pp/Po) •Starling’s Forces driving water movement Jv=KO (πc - πi)+KH(Pc -Pi) |
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