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. 2019 Apr 13;76(14):2663–2679. doi: 10.1007/s00018-019-03097-2

Table 6.

BRAF, ALK ErbB2 mutations combined: comparison of MD, SVM, SIFT, and PolyPhen2, against experiments

Mutation (all) MD prediction SVM prediction SIFT PolyPhen2
TPR 0.5946 0.8378 0.7568 0.9189
FPR 0.1111 0.2222 0.8333 0.9444
BACC 0.7417 0.8078 0.4617 0.4872