Table 3.

Pain

	Normal QST (n=35)	Abnormal QST (n=13)	p-Value
Overall Mean Pain
Past Month (VAS)	2.9 ± 3.0	2.9 ± 2.8	0.74
VOE Frequency
Previous 12 months
0	16 (45.7%)	3 (23.1%)
<3	15 (42.9%)	7 (53.8%)
≥3	4 (11.4%)	3 (23.1%)
Pain at Testing (VAS)
No Pain (0)	21 (60.0%)	9 (69.2%)
Mild (1 to 3)	9 (25.7%)	4 (30.8%)
Moderate (4 to 6)	5 (14.3%)	0
Severe (7 to 10)	0	0
Mechanical Pain
Cotton	0.1 ± 0.2	0.1 ± 0.2	0.40
Brush	0.1 ± 0.1	0.4 ± 0. 8	0.04*
Pinprick	1.8 ± 2.0	2.9 ± 1.7	0.05
Thermal Pain
Cold Sensation	0.1 ± 0.2	0.9 ± 1.7	0.01**
Warm Sensation	0.2 ± 0.5	1.8 ± 2.4	<0.0001**
Cold Pain	2.4 ± 2.2	2.7 ± 2.1	0.63
Heat Pain	3.5 ± 2.3	4.5 ± 1.7	0.14
Heat Pain Tolerance	5.3 ± 2.8	6.1 ± 2.8	0.39

VAS: 0 to 10 visual analog scale; VOE: number of vaso-occlusive episodes of acute pain requiring hospitalization the previous 12 months