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. 2019 Jun 22;18:145. doi: 10.1186/s12944-019-1065-9

Table 4.

Effects of linoleic acid in vitro and in vivo clinical trials

Disorder Study Possible mechanism of action References
Skin disorders Guinea pigs in vivo study Transformation of LA to 13-HODE and consequently the modulation of coetaneous hyperproliferation Ziboh (2000) [36]
Psoriasis Human in vivo study Reduce the rate of relapse and rebound Min Liu (2015)
Atherosclerosis Rabbits in vivo study Decrease LDL-cholesterol levels Larmo (2013) [15]