Table 1.
Baseline clinical characteristics of patients stratified by outcomes.
| Variables | mRS 0-2 | mRS 3-6 | p value | Alive | Dead | p value |
|---|---|---|---|---|---|---|
| 48 | 27 | 65 | 10 | |||
| Age (y) | 63.3 ± 10.5 | 73.3 ± 9.5 | <0.001 | 65.9 ± 11.3 | 73.4 ± 8.8 | 0.050 |
| Male (%) | 72.9 (35/48) | 70.4 (19/27) | 0.814 | 75.4 (49/65) | 50.0 (5/10) | 0.131 |
| HBP (%) | 72.9 (35/48) | 74.1 (20/27) | 0.913 | 69.2 (45/65) | 100.0 (10/10) | 0.054 |
| DM (%) | 20.8 (10/48) | 37.0 (10/27) | 0.128 | 21.5 (14/65) | 60.0 (6/10) | 0.019 |
| Smoking (%) | 45.8 (22/48) | 40.7 (11/27) | 0.670 | 46.2 (30/65) | 30.0 (3/10) | 0.497 |
| AF (%) | 16.7 (8/48) | 40.7 (11/27) | 0.021 | 21.5 (14/65) | 50.0 (5/10) | 0.110 |
| Previous stroke | 18.8 (9/48) | 37.0 (10/27) | 0.080 | 20.0 (13/65) | 60.0 (6/10) | 0.014 |
| NIHSS | 7 (3, 12) | 14 (9, 20) | <0.001 | 8 (4, 12) | 17 (10, 22) | 0.007 |
| OTT (min) | 185 (122, 222) | 150 (124, 192) | 0.178 | 164 (123, 220) | 164 (125, 198) | 0.969 |
| Baseline TK (pg/ml) | 40.4 (9.2, 82.9) | 8.4 (3.2, 23.3) | 0.002 | 34.5 (7.7, 61.8) | 3.7 (3.0, 13.3) | 0.012 |
| IV-tPA (%) | 91.7 (44/48) | 81.5 (22/27) | 0.269 | 89.2 (58/65) | 80.0 (8/10) | 0.344 |
| EVT (%) | 18.8 (9/48) | 37.0 (10/27) | 0.080 | 26.2 (17/65) | 20.0 (2/10) | 1.000 |
Abbreviations: HBP: hypertension; DM: diabetes mellitus; AF: atrial fibrillation; NIHSS: National Institutes of Health Stroke Scale; OTT: onset-to-treatment time; TK: tissue kallikrein; IV-tPA: intravenous tissue plasminogen activator; EVT: endovascular treatment.