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. 2019 Jun 3;2019:2612534. doi: 10.1155/2019/2612534

Figure 1.

Figure 1

Manipulation of the P2Y6 receptor-modulated sense of pain in neuropathic pain (NP) in rat models induced by CCI. (a) The operation of CCI surgery. Changes of PWT (b) and TWL (c). Data (mean ± SEM) were presented in all rats. S: sham-operated rats; M: CCI rats treated with MRS2578; C: CCI rats; U: CCI rats treated with UDP. Significance of pain behavioral changes was analyzed with two-way ANOVA followed by Holm–Sidak post hoc analysis (P < 0.05, vs the sham group; #P < 0.05, vs the CCI group).