Skip to main content
. 2019 Jun 3;2019:2612534. doi: 10.1155/2019/2612534

Figure 4.

Figure 4

The JAK/STAT signaling pathway was activated in CCI model rats. The mRNA levels of JAK2 (a) and STAT3 (b) were shown with mean ± SEM of IOD of JAK2/β-actin and STAT3/β-actin in all rats, n=5; the phosphorylated JAK2 (p-JAK2) (c) and STAT3 (p-STAT3) (d) levels were shown by the western blot and quantified by mean ± SEM of IOD of p-JAK2/β-actin and p-STAT3/β-actin in all rats, n=5, respectively. S: sham-operated rats; S: CCI rats; M: CCI rats treated with MRS2578; U: CCI rats treated with UDP. Comparisons of JAK2/STAT3 proteins and mRNA among four groups were analyzed with two-way ANOVA followed by Holm–Sidak post hoc analysis (∗P < 0.05, vs the sham group; #P < 0.05, vs the CCI group).