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. 2019 Jun 2;2019:8765954. doi: 10.1155/2019/8765954

Figure 1.

Figure 1

Effects of resveratrol and EX-527 pretreatment in lipopolysaccharide-induced acute hepatitis in D-galactosamine-sensitized rats (D-GalN/LPS) on the levels of (a) plasma ALT, (b) TBARS in homogenate and (c) SIRT1 expression. CO: control group; RES: 2.3 mg/kg resveratrol; D-GalN + LPS: 400 mg/kg D-galactosamine with 10 μg/kg lipopolysaccharide; RES + D-GalN + LPS: 2.3 mg/kg resveratrol + D-GalN + LPS; EX − 527 + RES + D-GalN + LPS: 1 mg/kg EX-527 plus a combination of previous substances. Data are expressed as means ± SEM (n = 6). aP < 0.05 versus CO. bP < 0.05 versus RES. cP < 0.05 versus D-GalN + LPS. dP < 0.05 versus RES + D-GalN + LPS (courtesy of Physiological Research, reference [140]).