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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Gynecol Oncol. 2019 Apr 17;154(1):228–235. doi: 10.1016/j.ygyno.2019.04.651

Figure 4: Cervical cancer-derived exosomes induce neurite outgrowth.

Figure 4:

(A) Representative fluorescent images of β-III tubulin staining (green) of PC12 cells treated with cervical cancer cell line derived exosomes. Scale bar, 20μm. (B) Quantitative PC12 neurite outgrowth assay results, showing both total neurites/well. Bars represent mean +/− SEM of n = 3 (exosome conditions), 6 (NGF), or 9 (PBS); *p < 0.05 vs. PBS alone; **p ≤ 0.005 vs. PBS alone; #p < 0.05 vs. all other cervical cancer exosomes. P-values reflect t-test results. (C) Western blot analysis of exosomes purified from the indicated cell lines for CD9 and CD81.