FIG 2.

Overview of KlebNet. (A) Network construction by cofunctional link inferences from diverse types of omics data and species and their integration. (B) Assessment of cofunctional links of KlebNet and individual component networks based on proportions of gene pairs annotated by same KEGG pathway terms, measured for each bin of 1,000 links from the most confident one. (C) Assessment of prediction efficacy of KlebNet based on retrieval rate of known pathway genes for individual KEGG pathways and random gene sets with the same size, measured by area under the receiver operating characteristic curve (AUROC) scores.