Figure 5.

Markers of tumorigenicity and regeneration from chemical liver injury and LV-FAH treated mice. (A) Alpha fetoprotein was increased in chemical liver injury, regardless of administration of LV (note logarithmic y-axis). (B) Percent of Ki-67 positive cells in random sections of liver from mice for each group. (C) Representative panels of Ki-67 immunohistochemistry from mice from each group. Ki-67 staining was markedly increased in response to chemical liver injury, regardless of LV co-administration. *p < 0.05 compared with control; **p < 0.05 compared with control and LV.