Table 2.

Impact of smoking history to prevalence and spectrum of EGFR mutation

Characteristics			EGFR genotypes				*p-value	EGFR mutation types						*p-value
			Wild types		Mutants		Common		Uncommon		Mix
Smoking history
	Ever smokers	89	38	43%	51	57%	0.0465	33	65%	8	16%	10	20%	0.0632
	Never smokers	51	13	25%	38	75%		27	71%	9	24%	2	5%
	Unknown	3
Age 55 years old and younger
	Ever smokers	51	24	47%	27	53%	0.0343	15	56%	7	26%	5	19%	0.139
	Never smokers	21	4	19%	17	81%		11	65%	6	35%	0	0%
Age older than 55 years old
	Ever smokers	38	14	37%	24	63%	0.6127	18	75%	1	4%	5	21%	0.421
	Never smokers	30	9	30%	21	70%		16	76%	3	14%	2	10%
Male
	Ever smokers	84	36	43%	48	57%	0.06	30	63%	8	17%	10	21%	0.429
	Never smokers	17	3	18%	14	82%		10	71%	3	21%	1	7%
Female
	Ever smokers	5	2	40%	3	60%	0.63	3	100%	0	0%	0	0%	1
	Never smokers	34	10	29%	24	71%		17	71%	6	25%	1	4%

Notes: * p-value <0.05 were statistically significant.