Table 3.
Multivariate logistic regression illustrating characteristics of Index cases of tuberculosis (TB) at Kisumu County, with Isoniazid Preventative Therapy (IPT)-eligible household contacts aged less than 5 years, 2014-2015, by IPT initiation status.
| Characteristics | IPT initiation/Total 47/238 (20%); | Crude Odds Ratio | P value | Adjusted Odds Ratio | P value |
|---|---|---|---|---|---|
| N. (%) | (95% CI) | (95% CI) | |||
| Age group | |||||
| <15 year | 3/18(17) | Ref | 0.5 | ||
| 15-29 years | 24/101(24) | 1.6 (0.4-5.8) | |||
| 30-45 years | 16/92(18) | 1.1 (0.3-4.1) | |||
| 45+ years | 4/30(14) | 0.8 (0.2-3.9) | |||
| Sex | |||||
| Male | 27/129(21) | 1.2 (0.6-2.3) | 0.5 | ||
| Female | 20/112(18) | Ref | |||
| Region | |||||
| Kisumu Urban | 26/167(16) | Ref | 0.02* | Ref | <0.01 |
| Kisumu rural | 21/74(28) | 2.2 (1.1-4.2) | 3.3 (1.6-6.8) | ||
| Smoked in the past 6 months | |||||
| Yes | 3/27(11) | 0.5 (0.1-1.7) | 0.3 | ||
| No | 44/214(21) | Ref | |||
| No. of household contacts aged <5 | |||||
| 1 | 24/159(15) | Ref | 0.01* | Ref | 0.06 |
| 2+ | 23/82(28) | 2.3 (1.2-4.4) | 1.9 (0.9-4.1) | ||
| Cough | |||||
| Present | 39/196(21) | 1.2 (0.5-2.7) | 0.7 | ||
| Absent | 8/45(18) | Ref | |||
| Smear Grade** | |||||
| Positive | 38/179(21) | 4.3 (0.9-18.6) | 0.03* | 5.1 (1.1-23.2) | 0.03 |
| Negative | 2/33(6) | Ref | Ref | ||
| Chest X ray results*** | |||||
| Normal | 4/22(18) | Ref | 0.3 | ||
| Abnormal cavitary | 17/69(25) | 1.5 (0.4-4.9) | |||
| Abnormal non cavitary | 12/78(15) | 0.8 (0.2-2.8) | |||
| HIV status | |||||
| Positive | 23/126(18) | 0.8 (0.4-1.6) | 0.6 | ||
| Negative | 24/115(21) | Ref |
*Entered into the multivariate logistic model
**missing information on sputum Smear results for 29 participants
***missing chest X ray results for 72 participants; TB type excluded due to no participants with extrapulmonary TB being initiated on IPT.