Table 5.
Multivariate logistic regression illustrating Characteristics household contacts aged less than 5 years of Index cases of tuberculosis (TB) at Kisumu County, 2014-2015 by Isoniazid Preventative Therapy (IPT) initiation status.
| Characteristics | IPT/Total IPT eligible 51/337 (15%); n/N (%) | Crude Odds Ratio (95% CI) | P value | Adjusted Odds Ratio (95% CI) | P value |
|---|---|---|---|---|---|
| Age group | |||||
| <2 year | 25/127(20) | 1.6 (0.7-3.7) | 0.18* | ||
| 2.0-3.9 years | 17/142(12) | 0.9 (0.4-2.1) | |||
| 4.0-4.9 years | 9/68(13) | Ref | |||
| Sex | |||||
| Male | 21/175(12) | Ref | 0.09* | Ref | 0.05 |
| Female | 30/162(19) | 1.7 (1.0-3.1) | 1.9 (1.0-3.6) | ||
| Region | |||||
| Kisumu Urban | 28/230(12) | Ref | 0.02* | Ref | <0.01 |
| Kiusmu Rural | 23/107(22) | 1.9 (1.1-3.6) | 2.6 (1.4-5.1) | ||
| Relationship to index case* | |||||
| Parent, sibling or grandparent | 41/222(19) | 2.4 (1.1-4.9) | 0.01* | 2.6 (1.2-5.5) | 0.02 |
| Other relation/non relative | 10/115(9) | Ref | Ref | ||
| Duration lived with index case | |||||
| <90 days | 14/107(13) | Ref | 0.5 | ||
| 90+days | 37/230(16) | 1.2 (0.6-2.4) | |||
| Contact No. of hours per day | |||||
| <8 hours | 14/104(13) | Ref | 0.6 | ||
| 8-24 hours | 37/233(16) | 1.2 (0.6-2.4) | |||
| Shared bedroom with index case | |||||
| Yes | 31/206(15) | 1.1 (0.6-1.9) | 0.9 | ||
| No | 20/131(15) | Ref | |||
| BCG | |||||
| Given scar present | 42/301(14) | Ref | 0.1* | Ref | 0.07 |
| Given scar absent | 8/28(29) | 2.5 (1.0-5.9) | 2.9 (1.2-7.5) | ||
| Not given | 1/8(13) | 0.9 (0.1-7.3) | 1.1 (0.1-10.3) | ||
| Ever received IPT | |||||
| Yes | 6/16(38) | 3.7 (1.3-10.6) | 0.01* | 2.9 (0.9-8.7) | 0.06 |
| No | 45/321(14) | Ref | Ref | ||
| HIV status** | |||||
| Positive | 2/13(15) | Ref | 0.9 | ||
| Negative | 41/281(15) | 1.1 (0.2-4.9) | |||
| TB Symptoms | |||||
| Present | 11/91(12) | Ref | 0.3 | ||
| Absent | 40/246(16) | 1.4 (0.7-2.9) |
*Entered into the multivariate logistic model
**Missing data for 43 contacts. History of prior TB treatment excluded due to no participants with prior TB being initiated on IPT.