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. 2019 Jun 12;10(1):827. doi: 10.4081/jphia.2019.827

Table 5.

Multivariate logistic regression illustrating Characteristics household contacts aged less than 5 years of Index cases of tuberculosis (TB) at Kisumu County, 2014-2015 by Isoniazid Preventative Therapy (IPT) initiation status.

Characteristics IPT/Total IPT eligible 51/337 (15%); n/N (%) Crude Odds Ratio (95% CI) P value Adjusted Odds Ratio (95% CI) P value
Age group
    <2 year 25/127(20) 1.6 (0.7-3.7) 0.18*
    2.0-3.9 years 17/142(12) 0.9 (0.4-2.1)
    4.0-4.9 years 9/68(13) Ref
Sex
    Male 21/175(12) Ref 0.09* Ref 0.05
    Female 30/162(19) 1.7 (1.0-3.1)   1.9 (1.0-3.6)
Region
    Kisumu Urban 28/230(12) Ref 0.02* Ref <0.01
    Kiusmu Rural 23/107(22) 1.9 (1.1-3.6)   2.6 (1.4-5.1)
Relationship to index case*
    Parent, sibling or grandparent 41/222(19) 2.4 (1.1-4.9) 0.01* 2.6 (1.2-5.5) 0.02
    Other relation/non relative 10/115(9) Ref Ref
Duration lived with index case
    <90 days 14/107(13) Ref 0.5
    90+days 37/230(16) 1.2 (0.6-2.4)
Contact No. of hours per day
    <8 hours 14/104(13) Ref 0.6
    8-24 hours 37/233(16) 1.2 (0.6-2.4)
Shared bedroom with index case
    Yes 31/206(15) 1.1 (0.6-1.9) 0.9
    No 20/131(15) Ref
BCG
    Given scar present 42/301(14) Ref 0.1* Ref 0.07
    Given scar absent 8/28(29) 2.5 (1.0-5.9) 2.9 (1.2-7.5)
    Not given 1/8(13) 0.9 (0.1-7.3) 1.1 (0.1-10.3)
Ever received IPT
    Yes 6/16(38) 3.7 (1.3-10.6) 0.01* 2.9 (0.9-8.7) 0.06
    No 45/321(14) Ref Ref
HIV status**
    Positive 2/13(15) Ref 0.9
    Negative 41/281(15) 1.1 (0.2-4.9)
TB Symptoms
    Present 11/91(12) Ref 0.3
    Absent 40/246(16) 1.4 (0.7-2.9)

*Entered into the multivariate logistic model

**Missing data for 43 contacts. History of prior TB treatment excluded due to no participants with prior TB being initiated on IPT.