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. 2019 Mar 1;30(5):717–728. doi: 10.1091/mbc.E18-10-0681

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FIGURE 2: — ComBat-adjusted data of gene expression across genotype and age conditions shows differential expression between Prdm9^+/+ and Prdm9^–/– samples. (A) Principal component 1 (PC1) vs. principal component 2 (PC2) from PCA of all ComBat-adjusted samples. Colors denote genotype, and shapes denote sample age, as indicated. (B, C) Shared and unique differentially expressed transcripts with decreased or increased abundance in Prdm9^–/– samples compared with Prdm9^+/+. FDR < 0.01 and LFC > 0.5 for B and C.