Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 20;29(5):486–495. doi: 10.1080/09537104.2017.1336210

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 The Author(s). Published by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 7. — Effects of inhibitors of RhoA signaling combined with podoplanin crosslinking on LEC migration. A) LEC settled onto a Transwell filter were treated with or without RhoA inhibitor CT04 (4 µg/ml), with or without antibodies that induced podoplanin crosslinking, with or without VEGF-C (300 ng/ml). The percentage of the LEC which had transmigrated after 24 h was analyzed. Data are mean ± SEM from three experiments. ANOVA showed significant effects of VEGF-C (p < 0.05) and treatment (p < 0.01). **=p < 0.01 compared to no treatment by Dunnet test for VEGF-C-treated cells. B) LEC settled onto a Transwell filter were treated with or without ROCK inhibitor Y27632 (100 µM), with or without antibodies that induced podoplanin crosslinking, with VEGF-C (300ng/ml). The percentage of the LEC which had transmigrated after 24 h was analyzed. Data are mean ± SEM from three or more experiments. ANOVA showed significant effect of treatment (p < 0.01). **=p < 0.01 compared to no treatment by Dunnett´s test.