TABLE 2:
Condition | Spindle shape | DNA position | aMTOCs position | Effect on size |
---|---|---|---|---|
HURP+ | 0.8 (ball) | 0.5 (center) | 1.65 (periph) | I unchanged |
NuMA+ | 0.75 (ball) | 0.55 (periph) | 1.35 (periph) | –10%A |
Eg5+ | 0.8 (ball) | 0.5 (center) | 1.5 (periph) | A unchanged |
Early Eg5 | 0.9 (inverted aster) | 0.45 (center) | 1.9 (periph) | +5%A |
MT stab+ | 0.75 (ball) | 0.6 (periph) | 1 (periph) | +25%A |
MT stab- | 0.7 (ball) | 0.6 (periph) | 1.5 (periph) | –20%A |
HSET-NuMA- | 0.9 (inverted aster) | 0.4 (center) | 2 (periph) | –15%L |
Early Eg5+ | 0.95 (inverted aster) | 0.45 (center) | 2.15 (periph) | –10%L |
For each perturbation, average values of around 15 simulations are given.
A stands for area and L for length.