Figure 4:

Association of maximum trough serum vancomycin levels with risk of incident AKI in multivariable adjusted Cox regression models in patients with different doses (< 4gms/day vs ≥ 4gms/day), duration (< 7 days vs ≥ 7 days), and number of antibiotics.

Models were adjusted for patient demographics, body mass index (BMI), comorbidities, baseline eGFR, mean arterial pressure, and nephrotoxic medication exposure.

Patients divided into 4 groups based on the highest recorded serum vancomycin trough level 1: < 10mg/L, 2: 10-15 mg/L, 3: 15.1-20 mg/L and 4: >20mg/L