Table 1.
Age | Sex | Genotype | Tibia | Femur | BF | Gast | TA | EDL | Sol | Quad |
---|---|---|---|---|---|---|---|---|---|---|
6 weeks | M | WT | 16.8 ± 0.2a | 13.1 ± 0.3a | 118 ± 4a | 107 ± 2a | 39 ± 1a | 8.3 ± 0.2a | 6.6 ± 0.3a | 163 ± 4a |
STAT5B−/− | 15.8 ± 0.2b | 12.0 ± 0.2b | 75 ± 3b | 73 ± 2bc | 27 ± 1b | 6.2 ± 0.5b | 5.6 ± 0.7abc | 106 ± 2b | ||
F | WT | 16.4 ± 0.2a | 12.7 ± 0.3a | 84 ± 4c | 78 ± 3b | 31 ± 1c | 6.3 ± 0.3b | 5.0 ± 0.2b | 119 ± 6c | |
STAT5B−/− | 15.9 ± 0.1b | 12.2 ± 0.1b | 71 ± 3b | 68 ± 2c | 26 ± 1b | 6.0 ± 0.4b | 4.4 ± 0.1c | 97 ± 2d | ||
12 weeks | M | WT | 18.2 ± 0.2a | 14.9 ± 0.1a | 162 ± 8a | 139 ± 2a | 49 ± 1a | 10.8 ± 0.3a | 8.0 ± 0.5a | 234 ± 5a |
STAT5B−/− | 16.6 ± 0.2b | 13.5 ± 0.2b | 110 ± 4b | 95 ± 3bc | 35 ± 1b | 7.4 ± 0.3b | 6.0 ± 0.3b | 143 ± 4b | ||
F | WT | 17.7 ± 0.2c | 14.5 ± 0.1c | 121 ± 2c | 101 ± 4b | 39 ± 2c | 10.1 ± 0.6a | 6.9 ± 0.5ab | 163 ± 4c | |
STAT5B−/− | 16.7 ± 0.2b | 13.6 ± 0.1b | 107 ± 4d | 89 ± 2c | 32 ± 1d | 7.7 ± 0.2b | 6.4 ± 0.5b | 135 ± 2b | ||
24 weeks | M | WT | 18.1 ± 0.1a | 15.0 ± 0.1a | 179 ± 4a | 148 ± 3a | 57 ± 2a | 12.3 ± 0.8a | 9.7 ± 0.5a | 245 ± 7a |
STAT5B−/− | 17.2 ± 0.2b | 14.1 ± 0.1b | 131 ± 7b | 115 ± 4b | 42 ± 1b | 8.9 ± 0.3b | 8.0 ± 0.3b | 173 ± 6b | ||
F | WT | 18.4 ± 0.2a | 15.3 ± 0.2a | 138 ± 9b | 117 ± 5b | 45 ± 2b | 9.6 ± 0.4b | 7.8 ± 0.3bc | 187 ± 6b | |
STAT5B−/− | 17.4 ± 0.1b | 14.4 ± 0.2b | 111 ± 9c | 111 ± 3b | 36 ± 2c | 7.5 ± 0.3c | 7.1 ± 0.2c | 168 ± 6c |
Values are presented as mean ± SEM. Abbreviations: BF biceps femoris, Gast gastrocnemius, TA tibialis anterior, EDL extensor digitorium longus, Sol soleus, Quad quadriceps. Unlike letters within each column denote significant differences (P < 0.05) between groups at each age only