Table 2.

Comparison of the results of ¹H NMR spectrum between controls and patients with severe extracranial carotid artery stenosis (CAS)

	Chemical shift (ppm)
Metabolite ID	Control (n = 65)	CAS (n = 65)	P value
Formate (8.46)	0.00235 ± 0.00046	0.00222 ± 0.00049	0.12583
Histidine (7.778)	0.00756 ± 0.00185	0.00764 ± 0.00167	0.80616
Phenyalanine (7.38)	0.00767 ± 0.00134	0.00781 ± 0.00132	0.56561
Phenyalanine (7.336)	0.01426 ± 0.00204	0.01485 ± 0.00243	0.13568
Tyrosine (7.20)	0.01159 ± 0.00179	0.01168 ± 0.00218	0.79284
Histidine (7.056)	0.00743 ± 0.00166	0.00726 ± 0.00145	0.53744
Tyrosine (6.906)	0.01066 ± 0.00164	0.01020 ± 0.00197	0.15681
Lactate (4.125)	0.09552 ± 0.02848	0.11547 ± 0.04951	0.00584
Creatinine (4.045)	0.02056 ± 0.00705	0.03025 ± 0.03457	0.03006
Glucose (3.248)	0.18253 ± 0.03440	0.16856 ± 0.04925	0.06328
Choline (3.205)	0.14156 ± 0.03223	0.12382 ± 0.03109	0.00177
Glutamine (2.47)	0.09644 ± 0.01241	0.09548 ± 0.01768	0.72204
Pyruvate (2.365)	0.03074 ± 0.00577	0.02922 ± 0.00602	0.14573
Lipid (2.23)	0.12925 ± 0.08064	0.12036 ± 0.06102	0.47984
N-acetylglycoprotein (2.054)	0.32462 ± 0.11493	0.31241 ± 0.08730	0.49632
Lipid (2.01)	0.34895 ± 0.11742	0.34877 ± 0.13591	0.99377
Acetate (1.915)	0.02723 ± 0.00443	0.02956 ± 0.01926	0.34458
Lipid (1.6)	0.25874 ± 0.16146	0.24437 ± 0.12969	0.57693
Lipid	0.24517 ± 0.14945	0.21435 ± 0.12022	0.19762
Lactate (1.332)	0.51526 ± 0.21607	0.54140 ± 0.20130	0.47661
Lipid (1.31)	3.17346 ± 1.64186	2.92170 ± 1.37389	0.34491
Valine (1.044)	0.03794 ± 0.01059	0.03926 ± 0.01097	0.48680
Isolecuine (1.005)	0.01209 ± 0.00389	0.01224 ± 0.00349	0.82135
Leucine (0.965)	0.02646 ± 0.00641	0.02479 ± 0.00567	0.11783
Lipid (0.90)	1.59928 ± 0.50784	1.42274 ± 0.44536	0.03709

Data are presented as mean ± SD. VIP variable importance in the projection