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Illustration of maximizing the area under the curve (AUC) when lesions from 2 different zones are combined. Red circles illustrate positive cases and blue cross illustrate negative cases. The AUC will be less than 1.0 if we simply combine cases from 2 zones. However, if we rescale the scores for zone 2 by 0.67 before mixing the cases, the AUC of 1.0 can be achieved.
