Table 2.
Treatment characteristics of all patients (n = 10).
Patient | Sex | Included
phase A |
Completed
study |
Total
carnitine start, mmol/l |
Lipids
chol, TG start, end study mmol/l |
Lactate
start, end study mmol/l |
IGF-1
start, end study nmol/l |
HbA1c
start, end study mmol/l |
Glucose level
phase A mmol/l mean, SD |
Glucose
level phase B mmol/l mean, SD |
Ketone
level phase A mmol/l mean, SD |
Ketone
level phase B mmol/l mean, SD |
Time on KD
days |
Diet after study
Type of diet |
OS
months |
Age
years |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | M | Yes | No | 50.9 | Chol: 6.20 TG: 0.82 | 1.2 | 16.7 | 36 | 4.5 (NA) | – | 3.50 (NA) | – | 15 | – | 18.4 | 65.5 |
2 | M | Yes | No | 33.2 | Chol: 4.3 TG: 0.77 Chol: 4.6 TG: 0.88 |
2.4 0.9 |
– | 32 31 |
4.6 (0.31) | 5.4 (0.76) | 4.98 (0.87) | 3.14 (0.83) |
96 | Modified Atkins Diet |
9.76 | 41.2 |
3 | M | Yes | Yes | 57.9 | Chol: 5.2 TG: 1.81 Chol: 4.7 TG: 1.06 |
1.2 0.7 |
17.2 21.9 |
33 23 |
4.6 (0.78) | 5.0 (0.70) | 4.84 (1.07) | 3.69 (1.15) |
97 | KD-MCT | 19.02 | 36.4 |
4 | M | Yes | Yes | 28.6 | Chol: 3.9 TG: 1.07 Chol: 4.7 TG: 2.41 |
1.2 1.3 |
30.4 17.9 |
29 25 |
4.4 (0.66) | 5.4 (0.81) | 4.97 (0.83) | 2.44 (1.03) |
97 | KD-MCT | 12.32 | 33.5 |
5 | M | Yes | Yes | 34.1 | Chol: 5.9 TG: 1.65 Chol: 5.9 TG: 1.48 |
1.8 1.2 |
12.4 13.2 |
39 31 |
4.8 (0.72) | 5.4 (0.57) | 5.39 (1.05) | 2.51 (0.98) |
98 | Modified Atkins Diet |
15.31 | 53.1 |
6 | F | Yes | No | 21.3 | Chol: 6.5 TG: 1.16 | 0.90 | 17.9 | 36 | 4.6 (0.71) | 5.3 (0.30) | 3.50 (0.65) | 1.38 (0.77) |
65 | Modified Atkins Diet |
9.89 | 62.9 |
7 | M | No | No | 31.6 | Chol: 4.7 TG:0.83 | 1.5 | 7.2 | – | – | – | – | – | – | – | 10.32 | 55.8 |
8 | M | Yes | Yes | 44.5 | Chol: 4.7 TG: 1.61 Chol: 3.9 TG: 1.92 |
– 0.9 |
20.6 35.9 |
40 29 |
4.7 (0.84) | 5.8 (0.59) | 4.47 (1.07) | 3.10 (1.09) |
99 | Modified Atkins Diet |
11.10 | 59.8 |
9 | M | Yes | Yes | 51.4 | Chol: 5.8 TG: 0.75 Chol: 7.4 TG: 1.80 |
1.3 – |
15.5 20.0 |
38 31 |
5.2 (0.47) | 5.0 (0.53) | 3.11 (0.66) | 3.27 (1.20) |
95 | KD-MCT | 17.71 | 53.8 |
10 | M | Yes | Yes | 34.4 | Chol: 5.9 TG: 0.66 Chol: 6.0 TG: 1.52 |
0.7 1.0 |
22.0 16.8 |
34 36 |
5.0 (0.63) | 5.0 (0.74) | 3.28 (0.84) | 2.19 (0.58) |
104 | KD-MCT | 12.78 | 55.5 |
Legenda:
Chol, cholesterol; F, female; HbA1c, glycated hemoglobulin; IGF-1, insulin growth factor 1; KD, ketogenic diet; M, male; MCT, medium-chain triglycerides; NA, not applicable; OS, overall survival; TG, triglyceride.