Table 1.
Demographics and clinical characteristics of 280 patients with lung adenocarcinoma and their epidermal growth factor mutation status
| Variable | Wild type (N=111) n (%) | EGFR mutation (N=169) n (%) | p value |
|---|---|---|---|
| Age | |||
| Mean ± SD | 65.36 ± 13.42 | 65.76 ± 13.57 | p=0.810 |
| Gender | |||
| Male | 67 (60.4%) | 60 (35.5%) | p<0.001 |
| Female | 44 (39.6%) | 109 (64.5%) | |
| Cigarette smoking status | |||
| Never-smoker | 50 (45.0%) | 131 (77.5%) | p<0.001 |
| Ever-smoker | 61 (55.0%) | 38 (22.5%) | |
| Stage | |||
| I+II | 26 (23.4%) | 47 (27.8%) | p=0.413 |
| III+IV | 85 (76.6%) | 122 (72.2%) | |
| Tumor T status | |||
| T1+T2 | 60 (54.1%) | 108 (63.9%) | p=0.100 |
| T3+T4 | 51 (45.9%) | 61 (36.1%) | |
| Lymph node status | |||
| Negative | 29 (26.1%) | 54 (32.0%) | p=0.296 |
| Positive | 82 (73.9%) | 115 (68.0%) | |
| Distant metastasis | |||
| Negative | 54 (48.6%) | 80 (47.3%) | p=0.830 |
| Positive | 57 (51.4%) | 89 (52.7%) | |
| Cell differentiation | |||
| Well | 8 (7.2%) | 21 (12.4%) | p<0.001 |
| Moderately | 80 (72.1%) | 138 (81.7%) | |
| Poorly | 23 (20.7%) | 10 (5.9%) |
EGFR, epidermal growth factor receptor.