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. Author manuscript; available in PMC: 2020 Jun 18.
Published in final edited form as: J Am Coll Cardiol. 2019 Jun 18;73(23):2946–2957. doi: 10.1016/j.jacc.2019.03.520

Figure 4. A regulatory-gene network identified in abdominal fat with major contribution to CAD heritability.

Figure 4.

This regulatory-gene network example contributing to 0.57% of CAD heritability was identified in gene expression data from visceral abdominal fat (VAF) from CAD patients in the STAGE study (11) and replicated in RNAseq data from the same tissue in STARNET.(12) Circles in the network illustration indicate individual genes. Squares indicate key disease drivers.