Figure 8.

HbO₂ abundance maps for healthy eyes. Presented with each eye is a colormap with patient condition, number of frames (data cubes) averaged to achieve the final map, and the spectral endmember result from NNMF. The right eye map for patient 1 is not available, and the left eye map for patient 3 was excluded. Blue arrows point to unique regions of interest, white arrows correspond to localizations of increased HbO₂ abundance, and black arrows point to regions devoid of unmixed HbO₂ (dropout). The white circle outlines foveal boundaries as interpreted by the maps. Yellow brackets demonstrate the bounds of center bands of lower HbO₂. The nasal side of the FOV exhibits large regions of HbO₂ dropout in patients 4 (OD and OS), 5 (OS), and 8 (OS), pictured in Figure 9 below. Hard exudates, floaters, and pigment abnormalities appear as sharp HbO₂ dropout as would be expected as these entities carry no vascular elements and hence, no HbO₂.