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. 2018 Dec 23;47(5):452–457. doi: 10.1002/dc.24122

Table 1.

Cytological findings of tall cell variant and conventional papillary thyroid carcinomas

Cytological findings Tall cell variant (n = 19) Conventional (n = 50) P
Background Foam cells 4 (21.1%) 11 (22.0%) N.S.
Lymphocytes 1 (5.3%) 16 (32.0%) .0274
Multinucleated giant cells 13 (68.4%) 28 (56.0%) N.S.
Watery colloid 0 (0.0%) 8 (16.0%) N.S.
Ropy colloid 6 (31.6%) 8 (16.0%) N.S.
Psammoma bodies 0 (0.0%) 2 (4.0%) N.S.
Arrangement Papillary 17 (89.5%) 41 (82.0%) N.S.
Follicular 0 (0.0%) 23 (46.0%) .0001
Monolayered sheet‐like 17 (89.5%) 49 (98.0%) N.S.
Trabecular 1 (5.3%) 0 (0.0%) N.S.
Solid 3 (15.8%) 0 (0.0%) .0185
Predominantly isolated 1 (5.3%) 6 (12.0%) N.S.
Palisaded 18 (94.7%) 8 (16.0%) <.0001
Cell shape Round or oval 6 (31.6%) 50 (100.0%) <.0001
Tall columnar 17 (89.5%) 18 (36.0%) .0001
Tombstone appearance 15(78.9%) 0 (0.0%) <.0001
Spindle‐like 13 (68.4%) 6 (12.0%) <.0001
Cytoplasm Densely stained 18 (94.7%) 25 (50.0%) .0006
Distinct cell border 17 (89.5%) 19(38.0%) .0001
Cytoplasmic elongation 17 (89.5%) 24 (48.0%) .0021
Septated intracytoplasmic vacuoles 0 (0.0%) 4 (8.0%) N.S.
Pseudokeratinization 5 (26.3%) 5 (10.0%) N.S.
Nucleus Ground glass appearance 1 (5.3%) 7 (14.0%) N.S.
Cytoplasmic inclusions 17 (89.5%) 41 (82.0%) N.S.
Soap bubble appearance 8 (42.1%) 14 (28.0%) N.S.
Grooves 19 (100.0%) 49 (98.0%) N.S.
Overlapping 13 (68.4%) 8 (16.0%) .0001
Various‐sized 1 (5.3%) 2 (4.0%) N.S.
Multilobated 2 (10.5%) 7 (14.0%) N.S.
Mitotic figure 3 (15.8%) 7 (14.0%) N.S.

N.S.: Not significant P > .05.

The characteristic findings for the tall cell variant are written in bold letters.