Figure 4.

Top row (a): Average quantitative MRI values in three tissue classes for healthy controls and patients (normal appearing tissue only); and bottom row (b): The relative difference (Z scaled to the control sample, with control range indicated in gray) in individual patients in the three tissue classes according to whether the tissue is normal appearing, perilesional or lesional. In this part of the figure, the shaded area represents ±2 standard deviations of the healthy control population values. Note the larger scale on the y‐axis for T1 relaxation time [Color figure can be viewed at http://wileyonlinelibrary.com]