Table 1.

Demographics and baseline disease characteristics in patients allocated to one of the five baseline NMSB categories defined by the NMSS total score cut‐off scores 0–20 (N = 28), 21–40 N = 41), 41–60 (N = 39), 61–80 (N = 36) and >80 (N = 89) and in the total post hoc analysis population (N = 233)

	Baseline NMSS total score burden
	0–20	21–40	41–60	61–80	>80	All
	(N = 28)	(N = 41)	(N = 39)	(N = 36)	(N = 89)	(N = 233)
Age (years)	64.6 ± 8.98	64.9 ± 9.12	66.4 ± 7.97	67.5 ± 9.10	66.6 ± 8.13	66.2 ± 8.52
BMI	24.8 ± 4.17	25.1 ± 4.40	26.5 ± 5.35	24.7 ± 4.10	25.2 ± 4.23	25.2 ± 4.40
Time since PD diagnosis (years)	13.4 ± 5.45	12.7 ± 4.47	11.7 ± 5.96	12.3 ± 7.58	12.6 ± 5.97	12.5 ± 5.93
UPDRS part IV modified item 32: Time with dyskinesia (h)	3.0 ± 2.45	3.8 ± 2.94	4.8 ± 3.50	5.3 ± 4.71	4.2 ± 3.86	4.2 ± 3.66
UPDRS part IV modified item 39: ‘Off’ time (h)	6.0 ± 2.32	5.7 ± 3.47	5.2 ± 2.69	4.9 ± 3.27	6.6 ± 2.87	5.9 ± 3.02
NMSS total score	10.8 ± 4.77	29.6 ± 6.41	51.9 ± 6.32	70.5 ± 5.17	112.8 ± 27.38	69.18 ± 42.13
Total PDQ‐8 score	35.9 ± 17.47	38.6 ± 16.79	45.2 ± 18.98	46.3 ± 12.33	54.3 ± 18.81	46.8 ± 18.63

BMI, body mass index; NMSB, NMSS burden; NMSS, Non‐Motor Symptom Scale; PDQ‐8, Parkinson's Disease Questionnaire 8 item; UPDRS, Unified Parkinson's Disease Rating Scale.

Values are presented as mean ± SD or percentage of patients.

NMSS total scores in bold represents the key NMS data reflecting rising NMS burden as pre cut off scores in top panel.