. 2019 May 30;8(7):829–837. doi: 10.1530/EC-19-0118
This work is licensed under a Table 1.
Basic characteristics, physical examination, aerobic capacity, muscle strength, Recent Physical Activity Questionnaire, biochemistry and body composition.
| Category | Variables | m.3243A>G | Controls | P value |
|---|---|---|---|---|
| Basic characteristics | Number (no.) | 23 | 23 | |
| Sex (Female/Male) | 10/13 | 10/13 | ||
| Age (years) | 30 (24–43) | 32 (27–46) | 0.67 | |
| Physical examination | Weight (kg) | 70 ± 19 | 77 ± 13 | 0.15 |
| Height (m) | 2 ± 0.1 | 2 ± 0.1 | 0.01 | |
| BMI (kg/m2) | 24 ± 5 | 24 ± 3 | 0.09 | |
| Systolic blood pressure (mmHg) | 126 ± 14 | 120 ± 10 | 0.09 | |
| Diastolic blood pressure (mmHg) | 77 ± 7 | 75 ± 8 | 0.51 | |
| Pulse (1/min) | 74 ± 11 | 66 ± 10 | 0.01 | |
| Waist circumference (cm) | 82 (78-98) | 86 (79-91) | 0.58 | |
| Hip circumference (cm) | 99 ± 9 | 103 ± 7 | 0.10 | |
| Aerobic capacity | VO2max (mL/kg/min) | 28 ± 8 | 36 ± 8 | <0.01 |
| Muscle strength | Handgrip muscle strength (kg) | 43 ± 14 | 46 ± 11 | 0.57 |
| Recent Physical Activity Questionnaire (RPAQ) | Total reported duration (hours) of activity times intensity (MET) (METhrs/day) | 20 (15–23) | 19 (14–26) | 0.62 |
| Total reported plus unaccounted duration hours) times intensity (MET) (METhrs/day) | 27 (23–32) | 27 (24–34) | 0.52 | |
| Total activity energy expenditure discounting resting (net METhrs/day) | 10 (6–15) | 10 (7–18) | 0.56 | |
| Sedentary behavior energy expenditure (METhrs/day) | 4.3 (2.8–9.1) | 4.0 (2.0–9.4) | 0.68 | |
| Light intensity energy expenditure (METhrs/day) | 0.0 (0.0–1.4) | 0.1 (0.0–8.5) | 0.24 | |
| Moderate intensity energy expenditure (METhrs/day) | 4.9 (2.2–9.7) | 4.2 (2.6–9.8) | 0.99 | |
| Vigorous intensity energy expenditure (METhrs/day) | 0.2 (0.0–2.9) | 1.3 (0.3–3.9) | 0.17 | |
| Biochemistry | HbA1c (mmol/mol) | 36 ± 4 | 34 ± 3 | 0.08 |
| Total cholesterol (mmol/L) | 4.5 ± 1.0 | 4.6 ± 0.8 | 0.80 | |
| HDL cholesterol (mmol/L) | 1.2 ± 0.4 | 1.4 ± 0.3 | 0.21 | |
| LDL cholesterol (mmol/L) | 2.8 ± 1.0 | 2.9 ± 0.7 | 0.82 | |
| Triglyceride (mmol/L) | 1.0 (0.7–1.4) | 0.8 (0.6–1.1) | 0.28 | |
| Creatinine (µmol/L) | 71 (65-84) | 77 (64-86) | 0.58 | |
| DXA | Whole-body fat mass (kg) | 21 ± 8 | 21 ± 7 | 0.99 |
| Whole-body lean mass (kg) | 50 ± 13 | 57 ± 11 | 0.05 | |
| Whole-body mass (kg) | 71 ± 18 | 78 ± 13 | 0.13 | |
| Total fat mass pct. (%) | 30 ± 8 | 27 ± 8 | 0.30 | |
| Total lean mass pct. (%) | 70 ± 8 | 73 ± 8 | 0.30 |
Mean ± s.d.; Median (IQR).