Table 2.
Genotype and Allele Frequencies for 3 HCRTR2 SNPs in Controls (n = 581) and CH Patients (n = 517)
| Controls % (n) | CH Patients % (n) | χ2 (df) | OR (95% CI) | P Value | P corr Value | |||
|---|---|---|---|---|---|---|---|---|
| rs3122156 | Genotype | TT | 51.4 (298) | 55.3 (286) | 5.620 (2) | .0602 | ||
| TG | 37.4 (217) | 37.5 (194) | ||||||
| GG | 11.2 (65) | 7.2 (37) | ||||||
| Allele | T | 70.1 (813) | 74.1 (766) | 4.129 (1) | 0.82 (0.68–0.99) | .0421 | .1263 | |
| G | 29.9 (347) | 25.9 (268) | ||||||
| rs2653342 | Genotype | GG | 73.2 (424) | 72.1 (373) | 1.951 (2) | .3770 | ||
| GA | 24.2 (140) | 26.3 (136) | ||||||
| AA | 2.6 (15) | 1.5 (8) | ||||||
| Allele | G | 85.3 (988) | 85.3 (882) | 0.002 (1) | 1.00 (0.79–1.27) | .9622 | ||
| A | 14.7 (170) | 14.7 (152) | ||||||
| rs2653349 | Genotype | GG | 66.3 (385) | 64.2 (332) | 0.854 (2) | .6525 | ||
| GA | 29.9 (174) | 32.5 (168) | ||||||
| AA | 3.8 (22) | 3.3 (17) | ||||||
| Allele | G | 81.2 (944) | 80.5 (832) | 0.165 (1) | 1.05 (0.85–1.30) | .6843 | ||
| A | 18.8 (218) | 19.5 (202) |
χ2, chi‐square; CH, cluster headache; CI, confidence interval; df, degrees of freedom; OR, odds ratio; P corr value, P value corrected for multiple testing.