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. 2019 Feb 28;10(4):880–889. doi: 10.1111/1759-7714.13018

Table 6.

Toxicities in the low‐BMI (BMI < 21.5 kg/m2) and high‐BMI groups (BMI ≥ 21.5 kg/m2)

All grades ≥ Grade 3
BMI ≥ 21.5 BMI < 21.5 BMI ≥ 21.5 BMI < 21.5
Variable N (%) N (%) P N (%) N (%) P
Leukopenia 5 (20.8%) 1 (4.3%) 0.10 0 (0%) 0 (0%)
Neutropenia 2 (8.3%) 1 (4.3%) 0.52 0 (0%) 0 (0%)
Anemia 3 (12.5%) 4 (17.4%) 0.48 0 (0%) 0 (0%)
Thrombocytopenia 6 (25.0%) 4 (17.4%) 0.39 1 (4.2%) 0 (0%) 0.51
Skin rash 10(41.2%) 5 (21.7%) 0.12 0 (0%) 0 (0%)
Liver dysfunction 3 (12.5%) 1 (4.3%) 0.32 0 (0%) 0 (0%)
Diarrhea 10(41.2%) 8 (34.8%) 0.43 0 (0%) 2 (8.7%) 0.23
Nausea 2 (8.3%) 4 (17.4%) 0.31 0 (0%) 0 (0%)
Anorexia 2 (8.3%) 5 (21.7%) 0.19 0 (0%) 1 (4.3%) 0.49
Constipation 1 (4.2%) 2 (8.7%) 0.48 0 (0%) 0 (0%)
Paronychia 4 (16.7%) 1 (4.3%) 0.52 0 (0%) 0 (0%)
Fatigue 6 (25.0%) 4 (17.4%) 0.39 0 (0%) 0 (0%)
Dry skin 1 (4.2%) 1 (4.3%) 0.74 0 (0%) 0 (0%)
Mucositis oral 3 (12.5%) 1 (4.3%) 0.32 0 (0%) 0 (0%)
Neuropathy 1 (4.2%) 0 (0%) 0.51 0 (0%) 0 (0%)
Conjunctivitis 1 (4.2%) 2 (8.7%) 0.48 0 (0%) 0 (0%)
Pneumonitis 2 (8.3%) 3 (13.0%) 0.48 0 (0%) 0 (0%)
Ileus 0 (0%) 1 (4.3%) 0.49 0 (0%) 0 (0%)
Edema 0 (0%) 1 (4.3%) 0.49 0 (0%) 0 (0%)
Cellulitis 0 (0%) 1 (4.3%) 0.49 0 (0%) 0 (0%)
Renal dysfunction 3 (12.5%) 0 (0%) 0.12 0 (0%) 0 (0%)
Fever 1 (4.3%) 1 (4.3%) 0.74 0 (0%) 0 (0%)

BMI, body mass index.