Table 1.
Liver 1 | Liver 2 | Liver 3 | Liver 4 | Liver 5 | Liver 6 | Liver 7 | |
---|---|---|---|---|---|---|---|
Age (y) | 42 | 63 | 47 | 52 | 46 | 62 | 63 |
DBD/DCD donor | DCD | DCD | DCD | DCD | DCD | DCD | DCD |
BMI / degree of steatosis | BMI 21 | BMI 28 | BMI 33, Histologically >60% steatosis | BMI 28 | BMI 27 | BMI 23 | BMI 25 |
Notably increased laboratory values in the donor | Peak AST 1676 U/L, peak ALT 1375 U/L, peak γGT 166 U/L | – | – | Peak γGT 340 U/L | Peak AST 161 U/L, peak ALT 270 U/L, peak γGT 254 U/L | Peak AST 201 U/L, peak ALT 175 U/L | – |
Intoxications | Binge drinking | – | – | Frequent alcohol consumption | Alcohol, heroin, speed cocaine, xtc | – | – |
dWIT (min)a | 29 | 23 | 30 | 33 | 27 | 35 | 25 |
CIT (min)b | 289 | 306 | 525 | 294 | 256 | 278 | 221 |
Donor hepatectomy time (min)c | 59 | 82 | 96 | 28 | 11 | 44 | 36 |
DRI30 | 2.53 | 2.82 | 2.46 | 2.92 | 2.50 | 3.75 | 3.03 |
ET‐DRI31 | 2.65 | 2.92 | 2.47 | 3.31 | 2.85 | 2.88 | 2.87 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body‐mass index; CIT, cold ischemia time; DBD, donation after brain death; DCD, donation after circulatory death; DRI, donor risk index; dWIT, donor warm ischemia time; ET‐DRI, Eurotransplant donor risk index; γGT, γ‐glutamyltransferase.
dWIT is defined as the time from withdrawal of mechanical support until the start of in situ cold perfusion.
CIT is defined as the time from in situ cold perfusion until the start of machine perfusion.
Donor hepatectomy time is defined as the time from in situ cold perfusion until the time of hepatectomy.