Table 2.
RT Administration According to Demographic, Clinical, and Pathological Characteristics
| WDLPS | Grade 1 to 2 DDLPS | Grade 3 DDLPS | |||||||
|---|---|---|---|---|---|---|---|---|---|
| % RT | P | SMD Before/After IPTWa | % RT | P a | SMD Before/After IPTWa | % RT | P | SMD Before/After IPTWa | |
| Sex | .020 | 0.394/0.061 | .416 | 0.115/0.053 | .854 | 0.069/<0.00 | |||
| Female | 26.7 | 31.7 | 33.3 | 1 | |||||
| Male | 14.3 | 37.0 | 36.5 | ||||||
| Patient age, ya | .020 | 0.367/<0.001 | .083 | 0.223/0.026 | .008 | 0.443/0.030 | |||
| ≤40 | 16.0 | 21.7 | 37.5 | ||||||
| 40‐50 | 27.3 | 34.1 | 52.6 | ||||||
| 50‐60 | 31.9 | 33.8 | 44.7 | ||||||
| 60‐70 | 11.3 | 33.3 | 28.9 | ||||||
| >70 | 9.3 | 45.5 | 14.3 | ||||||
| Tumor size, cma | .001 | 0.541/0.033 | .009 | 0.402/0.007 | <.001 | 0.961/0.047 | |||
| ≤10 | 33.3 | 56.2 | 63.6 | ||||||
| 10‐20 | 29.2 | 37.0 | 52.0 | ||||||
| 20‐30 | 18.8 | 37.6 | 26.8 | ||||||
| 30‐40 | 11.5 | 32.1 | 5.6 | ||||||
| >40 | 12.9 | 16.1 | 9.1 | ||||||
| FNCLCC grade | – | – | – | .551 | 0.101/0.053 | – | – | – | |
| 1 | 25.0 | ||||||||
| 2 | 35.2 | ||||||||
| 3 | – | ||||||||
| Completeness of surgical resection | 1 | 0.005/0.002 | .103 | 0.273/0.037 | .573 | 0.137/0.024 | |||
| R0/R1 | 19.6 | 35.9 | 36.2 | ||||||
| R2 | 20.0 | 9.1 | 26.7 | ||||||
| Multifocality | .381 | 0.189/0.001 | .275 | 0.185/0.022 | .620 | 0.090/<0.001 | |||
| No | 20.5 | 36.1 | 34.2 | ||||||
| Yes | 10.5 | 23.1 | 40.0 | ||||||
| Tumor rupture | 1 | 0.005/0.046 | .501 | 0.142/0.055 | .600 | 0.131/0.061 | |||
| No | 19.6 | 35.3 | 36.3 | ||||||
| Yes | 20.0 | 20.0 | 27.8 | ||||||
| Preoperative/postoperative chemotherapy | <.0001 | 0.611/0.023 | .025 | 0.302/0.015 | .271 | 0.224/0.055 | |||
| Not done | 16.7 | 31.7 | 32.4 | ||||||
| Done | 75.0 | 51.4 | 44.8 | ||||||
Abbreviations: DDLPS, dedifferentiated liposarcomas; FNCLCC, National Federation of Centers for the Fight Against Cancer (Federation Nationale des Centres de Lutte Contre le Cancer); IPTW, inverse probability of treatment weighting; R0, macroscopically complete surgical resection with negative microscopic margins; R1, macroscopically complete surgical resection with positive microscopic margins; R2; macroscopically incomplete surgical resection; RT, radiotherapy; SMD, standardized mean difference before/after inverse probability of treatment weighting; WDLPS, well‐differentiated liposarcomas.
P values were determined using the Mann‐Whitney‐Wilcoxon, the Kruskal‐Wallis, or the Fisher‐Freeman‐Halton Fisher tests, as appropriate.
Test and SMD were performed by comparing the distribution of the continuous variable in the 2 RT groups.