Table 5.

Grade 3 DDLPS Subgroup: Results From the Multivariable Cox Models

	Local Recurrence			Distant Metastasis			Overall Survival
	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
Age, y			.809			.935			.597
68 vs 54a	0.97	0.59‐1.60		0.95	0.59‐1.55		1.20	0.85‐1.70
Sex			.256			.636			.352
Male vs female	1.38	0.79‐2.39		1.12	0.71‐1.75		1.22	0.80‐1.85
Tumor size, cm			.405			.246			.736
30 vs 16a	1.39	0.85‐2.28		1.49	0.84‐2.62		1.09	0.76‐1.58
Completeness of surgical resection			.027			.975			.160
R2 vs R0/R1	2.32	1.10‐4.89		1.01	0.57‐1.79		1.51	0.85‐2.68
Tumor rupture			.004			.774			.082
Yes vs no	2.77	1.40‐5.49		1.08	0.62‐1.88		1.61	0.94‐2.75
Multifocality			.795			.324			.157
Yes vs no	1.09	0.56‐2.11		1.30	0.77‐2.18		1.43	0.87‐2.36

Abbreviations: 95% CI, 95% confidence interval; DDLPS, dedifferentiated liposarcomas; HR, hazard ratio; R0, macroscopically complete surgical resection with negative microscopic margins; R1, macroscopically complete surgical resection with positive microscopic margins; R2; macroscopically incomplete surgical resection.

P value was determined using a 2‐sided Wald test.

^aThe 2 values were the third and first quartiles, respectively, of the variable distribution.