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. 2019 Jan 31;28(2):55–62. doi: 10.1111/ajad.12862

Table 4.

Circumstances where OAT may not be preferred for OWS

OAT undesirable/inappropriate/inadequate OAT unavailable
• Mild OUD or physical dependence only ○ Patients with chronic pain • Rural and other areas without OAT access
• Prior to treatment with naltrexone a • Post overdose in naloxone‐treated patients
• Patients desiring opioid‐free therapy • Criminal justice system
• Tapering off OAT maintenance during the lowest dosages before discontinuation
• During OAT induction with buprenorphine when the previous opioid dose has been beyond about 80 mg of methadone daily

OAT, opioid agonist therapy; OUD, opioid use disorder; OWS, opioid withdrawal symptoms.

a

As a bridge to naltrexone (opioid‐receptor antagonist) during opioid‐free withdrawal or during/following OAT‐assisted withdrawal.