Table 3.

Andersen–Gill multivariate analysis with time depending covariables

Variable	Hazard Ratio	95% CI	p-value
ALS Unit	0.88	0.07–10.12	0.92
Gender	0.90	0.86–1.42	0.42
Bulbar onset	2.43	1.24–4.77	0.01
Family history	1.54	0.59–3.98	0.37
Riluzole	0.82	0.44–0.92	0.01
NIMV	2.7	1.94–3.8	0.12
Gastrostomy	1.83	1.29–2.58	<0.001
Age (years)	1.02	1.01–1.03	<0.001
Diagnostic delay (months)	0.99	0.99–1.0	0.71
Time of NIMV use (months)	0.94	0.93–0.94	<0.001
Time of gastrostomy use (months)	0.97	0.95–0.98	<0.001

Abbreviation: NIMV, noninvasive mechanical ventilation.