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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Cell Biochem. 2019 Apr 8;120(8):14044–14054. doi: 10.1002/jcb.28679

FIGURE 9.

FIGURE 9

Wnt inhibition decreases H2O2-induced tube formation in HRMECs. HRMECs were seeded into a Matrigel-coated six-well plate. These cells were then treated with vehicle, H2O2 (1 μM), or H2O2 (1 μM) presenting with compound 3289–8625 (50 μM). Cell images of five random views were taken after 6 hours (A) then analyzed by ImageJ (B). Tube formation stimulated by H2O2 induced Wnt signaling can be inhibited by compound 3289-8625 (*P < 0.05 and ****P < 0.001 via one-way ANOVA with the Dunnett correction). ANOVA, analysis of variance; HRMEC, human retinal microvascular endothelial cell