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TFAP4 promoted the invasion and metastasis of HCC cells by activating the PI3K/AKT signaling pathway. (a) Western blot detected the protein expression of key components of the PI3K/AKT signaling pathway. (b) Effects of inhibiting the AKT signaling pathway on invasion and migration of HCC cells (×100). (c) Western blot detected the expression of each protein in HCC cells treated with LY294002. ∗∗P < 0.01; ∗∗∗P < 0.001.
