Table 1.
Clinicopathological parameters | Cases (n) | TFAP4 expression | P value | |
---|---|---|---|---|
High | Low | |||
Age (year) | ||||
<60 | 176 | 85 | 91 | 0.536 |
≥60 | 41 | 22 | 19 | |
Gender | ||||
Male | 194 | 100 | 94 | 0.056 |
Female | 23 | 7 | 16 | |
HBsAg | ||||
Positive | 183 | 92 | 91 | 0.510 |
Negative | 34 | 15 | 19 | |
AFP (μg/l) | ||||
<400 | 135 | 65 | 70 | 0.661 |
≥400 | 82 | 42 | 40 | |
Tumor size (maximal diameter) | ||||
<5cm | 107 | 52 | 55 | 0.836 |
≥5cm | 110 | 55 | 55 | |
Number of tumors | ||||
Solitary | 181 | 87 | 94 | 0.412 |
Multiple | 36 | 20 | 16 | |
Encapsulation | ||||
Destructed | 74 | 40 | 34 | 0.315 |
Intact | 143 | 67 | 76 | |
Vascular invasion | ||||
Yes | 191 | 17 | 9 | 0.081 |
No | 26 | 90 | 101 | |
TNM stage | ||||
I-II | 184 | 92 | 92 | 0.631 |
III | 33 | 15 | 18 | |
BCLC stage | ||||
0-A | 177 | 84 | 93 | 0.251 |
B | 40 | 23 | 17 | |
Differentiated | ||||
I-II | 173 | 88 | 85 | 0.363 |
III-IV | 44 | 19 | 25 | |
Micrometastasis | ||||
Yes | 16 | 10 | 6 | 0.273 |
No | 201 | 97 | 104 |