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Irisin ameliorated the increased level of IL-6 and IL-1β in the hippocampal tissues of DM mice exposed to STZ. (a) Statistical bar graph showing irisin reduced the STZ-induced increased expression level of IL-6 in hippocampal tissues of DM mice. (b) Statistical bar graph showing irisin reduced the STZ-induced increased expression level of IL-1β in hippocampal tissues of DM mice. All data are expressed as means ± SEM. n = 6. ∗p < 0.05 vs. Cont; #p < 0.05 vs. STZ.
